AHCC® Immunomax®
Clinical Summary
Active hexose correlated compound (AHCC) is a nutritional product prepared from the mycelia of shiitake (Lentinus edodes) mushrooms. Like other mushrooms, it contains a mixture of polysaccharides, amino acids, and minerals. AHCC is also rich in alpha-1,4-glucan oligosaccharides, which are believed to enhance its biologic activities 5. Many people use AHCC to prevent and treat cancer.
AHCC is capable of improving the body’s immune system. It is an effective, well-absorbed, proprietary cultured shiitake mushroom extract, backed by over 30 human clinical studies. AHCC® is taken with the intention of improving the body’s immune system by enabling it early, while:
Enhancing the production of cytokines (immune-signaling molecules)*
Increasing the activity of certain white blood cells, to include: NK cells
DC cells*
T-cells*
Macrophages*
Animal models suggest that AHCC has antioxidant effects and may protect against disorders induced by oxidative stress 1. It also enhanced resistance against bacterial 3 and viral infections 4, and has anti-inflammatory effects against colitis 20. In healthy human subjects, AHCC improved T-cell immune responses 19; increased dendritic cell number and function 6; improved antibody response to influenza vaccine 21; and when used with Bifidobacterium longum, may modulate T regulatory and dendritic cell phenotypes to favour anti-inflammatory responses after antibiotic use 30.
Preclinical findings suggest anticancer effects 7 8 29. In cisplatin-treated mice, AHCC increased antitumor activity while reducing side effects 9, and showed synergistic effects with gemcitabine in pancreatic cancer cells 22. In humans, findings from a prospective cohort study suggest AHCC improved prognosis after curative resection of hepatocellular carcinoma 10. AHCC may also reduce chemotherapy-associated adverse effects in patients with advanced cancer 23, and in those with pancreatic ductal adenocarcinoma (PDAC) 25. However, an open-label multicenter study of patients with early stage prostate cancer found AHCC was ineffective in reducing prostate-specific antigen levels by 50% or more 11. More research is required into ongoing needs.
What is it used for
- Treat infections
- Treat cancer
- Improve liver function
- Chronic fatigue syndrome (CFS)
- Lyme disease (Lyme borreliosis)
- Post chemo
- Respiratory virus prevention and treatment
AHCC is capable to modulate the numbers and functions of immune cells including natural killer (NK) and T cells, promoting T cell function 31. Immunomax capsules.
While AHCC is also used for other reasons, there isn’t enough research for all possible applications. Talk with your doctor before taking AHCC.
No supplement will cure or prevent disease. With the 2019 coronavirus COVID-19 pandemic, it’s especially important to understand that no supplement, diet, or other lifestyle modification other than physical distancing, also known as social distancing, and proper hygiene practices can protect you from COVID-19. Currently, no research supports the use of any supplement to protect against COVID-19 specifically.
Manufacturer’s product description
This unique super strong product manufactured by Hankintatukku (Finland) provides 250 mg of AHCC® per capsule.
AHCC® is manufactured by proprietary cell culture process for its immunomodulatory function.
The main active components of Immunomax are polysaccharides (α-glucan and b-1-3 glucan) and glycoproteins derived from AHCC ® which is a well-controlled substance obtained by reacting specific enzymatic reaction with basidomycetes mycelia.
AHCC® is effective in stimulating and enhancing the natural immunomodulatory function of the body (stimulates the production of NK cells, killer T-cells, and cytokines).
AHCC® is well-studied and has not reported any toxicity or side effects.
Free from lactose, sweeteners, gluten and yeast.
Has not reported any toxicity or side effects.
Hankintatukku Oy
Hankintatukku as manufacturer of Immunomax AHCC complies with guidelines of Good Manufacturing Practice (GMP) for pharmaceutical factories.
GMP guidelines define the various stages of the production and the associated inspection system linked with them. The purpose of GMP is to ensure high quality and absolute safety of the products.
GMP quality and safety system covers all the company’s operations. The observation of GMP is supervised by the Finnish Medicine Agency FIMEA.
Hankintatukku’s product development and manufacturing are guided by the specific Scientific Advisory Board. The scientific members of the board are internationally acknowledged experts from special fields such as botany, organic chemistry, pharmaceutical technology, medicine and nutrition.
Explore more than 200 other Hankintatukku products on www.immunesupp.com.
Many patients use AHCC to prevent and treat cancer. Animal models suggest that AHCC has antioxidant effects and may protect against disorders induced by oxidative stress. It also enhanced resistance against bacterial and viral infections, and has anti-inflammatory effects against colitis.
Warnings and precautions for use of Immunomax AHCC
AHCC is POSSIBLY SAFE when taken by mouth appropriately in medicinal amounts. Doses of AHCC ranging from 4.5 to 6 grams daily have been used safely for up to 6 months. A lower dose (3 grams daily) appears to be safe when it is used for up to 9 years.
Precautions:
Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking AHCC if you are pregnant or breast feeding. Stay on the safe side and avoid use.
Interactions:
We currently have no information for ACTIVE HEXOSE CORRELATED COMPOUND (AHCC)
Autoimmune diseases: AHCC seems to increase immune function and might make autoimmune diseases worse. People with autoimmune diseases, such as multiple sclerosis, systemic lupus erythematosus (SLE), or rheumatoid arthritis (RA), should avoid AHCC or talk to a healthcare professional before using it.
- Not suitable for pregnant or breastfeeding women.
- Do not exceed recommended daily dose.
- Food supplements should not replace a balanced diet and healthy lifestyle.
- Keep out of sight and reach of children.
If you’re considering the use of AHCC for a chronic condition, make sure to consult your physician. Self-treating a chronic condition with AHCC and avoiding or delaying standard care may have serious consequences.
Treatment for HPV infections.
The benefits of AHCC in Cancer (video)